Spravato (esketamine)

Do you have treatment resistant depression? Have you taken two or more oral antidepressants and still experience symptoms of depression? SPRAVATO offers a different approach. SPRAVATO is a nasal spray treatment that acts on the pathway in the brain where glutamate, a brain chemical, works with other brain chemicals to balance well being and depression. During a SPRAVATO session, a medical provider monitors the patient for two hours after treatment. During this session, you might experience:

• Dissociation
• Dizziness
• Nausea
• Feeling Sleepy
• Spinning sensation
• Decreased Feeling of Sensitivity (numbness)
• Feeling Anxious
• Lack of Energy
• Increased Blood Pressure
• Vomiting
• Feeling Drunk
• Feeling very Happy or Excited.

For this reason, after SPRAVATO is administered, there will be an observation period of at least two hours, during which you will rest comfortably while a health care provider monitors you for possible side effects Because of possible side effects affecting mental alertness and motor coordination, you won't be able to drive, operate machinery or do anything where you need to be completely alert until the next day. You'll need a plan for rides on treatment days. SPRAVATO is always taken at a certified treatment center.

What does treatment look like?

• SPRAVATO is taken with an oral anti-depressant.
• You administer SPRAVATO nasal spray yourself under the supervision of a healthcare provider at a certified SPRAVATO treatment center.
• SPRAVATO is taken twice a week for the first four weeks.
• After the first four weeks, you and your doctor will discuss and determine if treatment should be continued and the dose and how often you'll receive it.

Talk with our Nurse Practitioner, Brittany Bullard FNP, PMHNP, to see if this treatment is right for you!